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LY2835219 mesylate
CAS No. 1231930-82-7
LY2835219 mesylate ( Abemaciclib )
Catalog No. M10916 CAS No. 1231930-82-7
LY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 27 | In Stock |
|
| 5MG | 45 | In Stock |
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| 10MG | 65 | In Stock |
|
| 25MG | 77 | In Stock |
|
| 50MG | 88 | In Stock |
|
| 100MG | 113 | In Stock |
|
| 200MG | 141 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLY2835219 mesylate
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NoteResearch use only, not for human use.
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Brief DescriptionLY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.
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DescriptionLY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.
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SynonymsAbemaciclib
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PathwayAngiogenesis
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TargetCDK
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RecptorCDK4; CDK6
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1231930-82-7
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Formula Weight602.70
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Molecular FormulaC27H32F2N8·CH4O3S
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Purity>98%(HPLC)
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SolubilityEthanol: 24 mg/mL (39.82 mM); Water: 100 mg/mL (165.92 mM); DMSO: 83 mg/mL (137.71 mM)
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SMILESCS(O)(=O)=O.CCN1CCN(CC2=CN=C(NC3=NC=C(F)C(=N3)C3=CC4=C(N=C(C)N4C(C)C)C(F)=C3)C=C2)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Sanchez-Martinez et al. Mol Y Ther, 2011,10(11 Suppl), Abstract nr B234.
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